A drug called hydroxyurea has long been used to fight sickle cell disease, but some female patients may have shied away from it due to concerns that it could harm future fertility.

Those fears may be unfounded: A new study finds that hydroxyurea has no effect on what's known as "ovarian reserve" -- the number of healthy eggs a girl ...

Women who've undergone stem cell treatments for blood cancers, or for illnesses such as sickle cell disease, can successfully bring a pregnancy to term, new research shows.

The German findings run counter to the perceived wisdom on this issue: Many such patients are typically told that safe pregnancies are out of the question if they've undergone what's known as "allogeneic hemat...

There's more good news in the battle against sickle cell disease, with another trial finding CRISPR gene-editing therapy delivering impressive results for patients.

"It's encouraging that this gene-editing treatment continues to show promising efficacy for sickle cell patien...

Casgevy, a groundbreaking treatment that was approved to treat sickle cell disease in December, was given the U.S. Food and Drug Administration's blessing on Tuesday to treat another inherited blood disorder.

Casgevy is the first CRISPR-based medicine, where gene editing is used to develop the treatment, to be approved for use in the United States.

The one-time dose permanently chan...

Sickle cell disease is one of many chronic health conditions that dramatically increases the risk of hospitalization and death in people infected by COVID-19.

Unfortunately, folks with sickle cell disease are much less likely to have received the best protection available to them -- a COVID vaccine.

Completion of the initial two-dose COVID vaccination series is nearly two times lowe...

The U.S. Food and Drug Administration on Friday approved two milestone gene therapies for sickle cell disease, including the first treatment ever approved that uses gene-editing technology.

Casgevy, developed by Vertex Pharmaceuticals of Boston and CRISPR Therapeutics of Switzerland, is the first medicine available in the United States to treat a genetic disease using the CRISPR gene-edit...

A new gene therapy for sickle cell disease was deemed safe by a U.S. Food and Drug Administration advisory panel on Tuesday, paving the way for full approval by early December.

The FDA had already decided that the therapy, known as exa-cel, was effective.

Developed by Vertex Pharmaceuticals of Boston and CRISPR Therapeutics of Switzerland, exa-cel frees patients from the excruciatin...

Patients with sickle cell disease may soon have two new treatments to try.

On Tuesday, a U.S. Food and Drug Administration advisory committee will weigh the merits of a new gene therapy for the painful, inherited condition, which typically strikes Black people.

The agency is expected to make a decision on that therapy in early December, and it also plans to decide on a second new tr...

A type of gene therapy that precisely "edits" a key bit of DNA might offer a new way to treat sickle cell disease -- a painful inherited condition that largely strikes Black children and adults.

That's according to a new study in the New England Journal of Medicine desc...

A clinical trial that's attempting to discover a cure for sickle cell disease has found a new gene therapy to be safe and successful in four patients.

Two of the patients were treated at Cleveland Clinic Children's in Ohio, and doctors there are hopeful that their positive results will be borne out in future research.

"New treatments like this are critical for people who have sickle...

An exceptionally pricey gene therapy cure for sickle cell disease could soon be available, but it's not clear whether insurance companies will balk at the cost and deny coverage.

On the surface, the gene therapy does not appear as cost-effective as the grinding medical care that sickle cell patients now receive, according to a new analysis.

Gene therapy applied just once to a sickle...

While joint reconstruction surgeries are fairly common, they may be anything but routine for people with sickle cell disease.

Patients with the blood disorder who undergo total knee replacement are at a higher risk for complications than other patients, according to a new large-scale study.

"SCD patients undergoing total knee replacement need a multidisciplinary approach and ma...

Too few children with sickle cell anemia are getting the recommended screening tests for stroke, a common complication of this disease, a new government report finds.

What's more, many aren't receiving